What is HLA-B27?
a genetic marker for a certain spine condition
HLA-B27 is a gene variant linked to ankylosing spondylitis and certain other autoimmune diseases. The test is done once in a lifetime.
About 8 percent of the population is HLA-B27 positive. Being positive does not mean having the disease - it means raised risk. The result is interpreted in light of symptoms.
Test facts
- Sample
- Whole blood
- Fasting
- No fasting needed
- Turnaround
- 10 days
What does low HLA-B27 mean?
A negative result makes ankylosing spondylitis less likely.
What does high HLA-B27 mean?
A positive result indicates raised risk of ankylosing spondylitis and certain other rheumatological diseases.
More markers in the same area
Launching in Stockholm in 2026.
Want to know when you can order?
This is general information about the marker, not an assessment of your values and not medical advice. Last updated: May 2026.